Biochemical parameters of mild, moderate & severe COVID-19 patients

Background and objectives: Coronavirus disease 2019 (COVID-19) is affecting millions of people world-wide. It caused by the severe acute respiratory syndrome corona virus 2(SARS-CoV-2). The laboratory findings are very important to assess progress disease. present study aimed discuss biochemical parameters among mild, moderate COVID-19 patients. Materials methods: A cross sectional were conducted in Department Physiology, Dhaka Medical College, from January 2020 December 2020. After obtaining ethical clearance, a total 100 real time-polymerase chain reaction (RT-PCR) positive patients selected College Hospital. With all aseptic precautions, 10 ml venous blood was collected ante-cubital vein. D-dimer, prothrombin time, C-reactive protein (CRP), lactate dehydrogenase (LDH), serum ferritin, random glucose (RBG), creatinine, glutamic-pyruvic-transaminase (SGPT) albumin measured Laboratory Medicine, Hospital, Dhaka. CRP Immunoturbidimetric method, ferritin estimated Chemiluminescent microparticle immunoassay. STA-neoplastine CI plus used with STA-R analyzer for determination time. D-dimer Immunofluorescence Assay method. Serum LDH Dimention clinical chemistry system, bromocresol purple dye binding creatinine Jaffe alkaline picrate method SGPT colourmetric (IFCC 1980) RBG enzymatic colorimetric (GOD-PAP). Data recorded pre-designed structured data collection form. For statistical analysis, ANOVA followed Bonferroni test, Chi square Spearman’s rho correlation coefficient test performed as applicable using SPSS windows version 25.0. Results: By analyzing RT-PCR revealed evaluation shows severity significantly associated CRP, SGPT, S. Creatinine, LDH, Ferritin, & Prothrombin No significant association found Albumin. correction following compare between each group. reveals statistically strong Ferritin mild Conclusion: This showed illness that higher group comparison groups. So, comprehensive analysis will be helpful early identification better management